CPT procedure code

81406

Medicare payment

$282.88

2026 Clinical Laboratory Fee Schedule

Source: CMS Clinical Laboratory Fee Schedule (2026). CMS fee schedules ↗ · PFS status indicator X

National amount before geographic adjustment. Your MAC's locality rate will differ.

Code definition

Code

81406

Code system

CPT (Current Procedural Terminology)

This CPT code is not in our curated reference. CPT codes are maintained by the American Medical Association (AMA). Full descriptions require an AMA license.

Category

Short description sourced from CMS publicly available fee schedule data. Full CPT descriptions are copyright AMA. Not a substitute for the official CPT codebook.

Policy activity for CPT 81406

CLV Intelligence is tracking 14 policy changes that cite CPT 81406 most recently on 2026-06-05, drawn from 13 LCD/NCD coverage updates and 1 proposed LCD. The changes span Clinical Laboratory, Multi-specialty and Oncology. 4 are flagged critical or high priority.

LCD/NCD coverage updates
13
proposed LCD
1

Counts reflect the source documents CLV has matched to CPT 81406 to date; each links to the government publication that is authoritative. Monitored daily from CMS, the Federal Register, and Medicare Administrative Contractor publications.

Policy changes matched to 81406

Matched to this code by CLV analysis of each policy. The linked source document is authoritative.

LCD L36021: MolDX: Molecular Diagnostic Tests (MDT) — CGS

Clinical Laboratory · LCD-L36021

Government source· CMS / MACverify ↗
High

Full analysis available with a CLV subscription.

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LCD L36256: MolDX: Molecular Diagnostic Tests (MDT) — Noridian

Clinical Laboratory · LCD-L36256

Government source· CMS / MACverify ↗
High

Full analysis available with a CLV subscription.

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LCD L35160: MolDX: Molecular Diagnostic Tests (MDT) — Noridian

Clinical Laboratory · LCD-L35160

Government source· CMS / MACverify ↗
High

Full analysis available with a CLV subscription.

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LCD L38337: MolDX: Pharmacogenomics Testing — Noridian

Clinical Laboratory · LCD-L38337

Government source· CMS / MACverify ↗
Routine

Full analysis available with a CLV subscription.

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LCD L39040: MolDX: Lab-Developed Tests for Inherited Cancer Syndromes in Patients with Cancer — WPS

Oncology · LCD-L39040

Government source· CMS / MACverify ↗
Routine

Full analysis available with a CLV subscription.

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LCD L39017: MolDX: Lab-Developed Tests for Inherited Cancer Syndromes in Patients with Cancer — CGS

Oncology · LCD-L39017

Government source· CMS / MACverify ↗
Routine

Full analysis available with a CLV subscription.

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LCD L38394: MolDX: Pharmacogenomics Testing — CGS

Clinical Laboratory · LCD-L38394

Government source· CMS / MACverify ↗
Routine

Full analysis available with a CLV subscription.

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LCD L38335: MolDX: Pharmacogenomics Testing — Noridian

Clinical Laboratory · LCD-L38335

Government source· CMS / MACverify ↗
Routine

Full analysis available with a CLV subscription.

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Proposed LCD DL35000: Molecular Pathology Procedures — NGS

Multi-specialty · LCD-DL35000

Government source· CMS / MACverify ↗
High

Full analysis available with a CLV subscription.

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LCD L38972: MolDX: Lab-Developed Tests for Inherited Cancer Syndromes in Patients with Cancer — Noridian

Oncology · LCD-L38972

Government source· CMS / MACverify ↗
Routine

Full analysis available with a CLV subscription.

View alert

Audit documentation

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