Source: CMS Clinical Laboratory Fee Schedule (2026). CMS fee schedules ↗ · PFS status indicator X
National amount before geographic adjustment. Your MAC's locality rate will differ.
Code definition
Code
81450
Code system
CPT (Current Procedural Terminology)
This CPT code is not in our curated reference. CPT codes are maintained by the American Medical Association (AMA). Full descriptions require an AMA license.
Category
—
Short description sourced from CMS publicly available fee schedule data. Full CPT descriptions are copyright AMA. Not a substitute for the official CPT codebook.
Policy activity for CPT 81450
CLV Intelligence is tracking 24 policy changes that cite CPT 81450 between 2026-06-05 and 2026-08-27, drawn from 21 LCD/NCD coverage updates and 3 proposed LCDs. The changes span Clinical Laboratory, Hematology and Oncology. 15 are flagged critical or high priority.
LCD/NCD coverage updates
21
proposed LCDs
3
Counts reflect the source documents CLV has matched to CPT 81450 to date; each links to the government publication that is authoritative. Monitored daily from CMS, the Federal Register, and Medicare Administrative Contractor publications.
Policy changes matched to 81450
Matched to this code by CLV analysis of each policy. The linked source document is authoritative.
Proposed LCD DL40425: MolDX: Next-Generation Sequencing for Hematologic Malignancies and Suspected Hematologic Malignancies — Palmetto GBA
The Tripwire Audit Pack exports 12 months of single-specialty policy-change history — every alert with a link to its government source document, as a formatted PDF for compliance distribution plus a machine-readable CSV. Delivered automatically after payment. No account, no call.