CPT procedure code

81455

Medicare payment

$2,919.60

2026 Clinical Laboratory Fee Schedule

Source: CMS Clinical Laboratory Fee Schedule (2026). CMS fee schedules ↗ · PFS status indicator X

National amount before geographic adjustment. Your MAC's locality rate will differ.

Code definition

Code

81455

Code system

CPT (Current Procedural Terminology)

This CPT code is not in our curated reference. CPT codes are maintained by the American Medical Association (AMA). Full descriptions require an AMA license.

Category

Short description sourced from CMS publicly available fee schedule data. Full CPT descriptions are copyright AMA. Not a substitute for the official CPT codebook.

Policy activity for CPT 81455

CLV Intelligence is tracking 13 policy changes that cite CPT 81455 between 2026-06-05 and 2026-08-27, drawn from 9 LCD/NCD coverage updates and 4 proposed LCDs. The changes span Clinical Laboratory and Oncology. 11 are flagged critical or high priority.

LCD/NCD coverage updates
9
proposed LCDs
4

Counts reflect the source documents CLV has matched to CPT 81455 to date; each links to the government publication that is authoritative. Monitored daily from CMS, the Federal Register, and Medicare Administrative Contractor publications.

Policy changes matched to 81455

Matched to this code by CLV analysis of each policy. The linked source document is authoritative.

Proposed LCD DL40431: MolDX: Genome-Wide Molecular Methodologies for the Detection of Copy Number Alterations and Structural Variants in Hematologic Neoplasms — CGS

Oncology · LCD-DL40431

Government source· CMS / MACverify ↗
Critical

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Proposed LCD DL40427: MolDX: Next-Generation Sequencing for Hematologic Malignancies and Suspected Hematologic Malignancies — Noridian

Oncology · LCD-DL40427

Government source· CMS / MACverify ↗
Critical

Full analysis available with a CLV subscription.

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Proposed LCD DL40451: MolDX: Next-Generation Sequencing for Hematologic Malignancies and Suspected Hematologic Malignancies — CGS

Oncology · LCD-DL40451

Government source· CMS / MACverify ↗
Critical

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Proposed LCD DL40425: MolDX: Next-Generation Sequencing for Hematologic Malignancies and Suspected Hematologic Malignancies — Palmetto GBA

Oncology · LCD-DL40425

Government source· CMS / MACverify ↗
Critical

Full analysis available with a CLV subscription.

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LCD L36256: MolDX: Molecular Diagnostic Tests (MDT) — Noridian

Clinical Laboratory · LCD-L36256

Government source· CMS / MACverify ↗
High

Full analysis available with a CLV subscription.

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LCD L36021: MolDX: Molecular Diagnostic Tests (MDT) — CGS

Clinical Laboratory · LCD-L36021

Government source· CMS / MACverify ↗
High

Full analysis available with a CLV subscription.

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LCD L35160: MolDX: Molecular Diagnostic Tests (MDT) — Noridian

Clinical Laboratory · LCD-L35160

Government source· CMS / MACverify ↗
High

Full analysis available with a CLV subscription.

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LCD L40226: MolDX: Non-Next Generation Sequencing Targeted Molecular Panel Tests for Targeted Therapy in Cancer — CGS

Oncology · LCD-L40226

Government source· CMS / MACverify ↗
High

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LCD L40278: MolDX: Non-Next Generation Sequencing Targeted Molecular Panel Tests for Targeted Therapy in Cancer — WPS

Oncology · LCD-L40278

Government source· CMS / MACverify ↗
High

Full analysis available with a CLV subscription.

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LCD L40222: MolDX: Non-Next Generation Sequencing Targeted Molecular Panel Tests for Targeted Therapy in Cancer — Noridian

Clinical Laboratory · LCD-L40222

Government source· CMS / MACverify ↗
High

Full analysis available with a CLV subscription.

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Audit documentation

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