CPT procedure code

81540

Medicare payment

$3,750.00

2026 Clinical Laboratory Fee Schedule

Source: CMS Clinical Laboratory Fee Schedule (2026). CMS fee schedules ↗ · PFS status indicator X

National amount before geographic adjustment. Your MAC's locality rate will differ.

Code definition

Code

81540

Code system

CPT (Current Procedural Terminology)

This CPT code is not in our curated reference. CPT codes are maintained by the American Medical Association (AMA). Full descriptions require an AMA license.

Category

Short description sourced from CMS publicly available fee schedule data. Full CPT descriptions are copyright AMA. Not a substitute for the official CPT codebook.

Policy activity for CPT 81540

CLV Intelligence is tracking 5 policy changes that cite CPT 81540 most recently on 2026-06-05, drawn from 4 LCD/NCD coverage updates and 1 proposed LCD. The changes span Clinical Laboratory and Multi-specialty. 4 are flagged critical or high priority.

LCD/NCD coverage updates
4
proposed LCD
1

Counts reflect the source documents CLV has matched to CPT 81540 to date; each links to the government publication that is authoritative. Monitored daily from CMS, the Federal Register, and Medicare Administrative Contractor publications.

Policy changes matched to 81540

Matched to this code by CLV analysis of each policy. The linked source document is authoritative.

LCD L36021: MolDX: Molecular Diagnostic Tests (MDT) — CGS

Clinical Laboratory · LCD-L36021

Government source· CMS / MACverify ↗
High

Full analysis available with a CLV subscription.

View alert

LCD L36256: MolDX: Molecular Diagnostic Tests (MDT) — Noridian

Clinical Laboratory · LCD-L36256

Government source· CMS / MACverify ↗
High

Full analysis available with a CLV subscription.

View alert

LCD L35160: MolDX: Molecular Diagnostic Tests (MDT) — Noridian

Clinical Laboratory · LCD-L35160

Government source· CMS / MACverify ↗
High

Full analysis available with a CLV subscription.

View alert

Proposed LCD DL35000: Molecular Pathology Procedures — NGS

Multi-specialty · LCD-DL35000

Government source· CMS / MACverify ↗
High

Full analysis available with a CLV subscription.

View alert

LCD L35000: Molecular Pathology Procedures — NGS

Clinical Laboratory · LCD-L35000

Government source· CMS / MACverify ↗
Routine

Full analysis available with a CLV subscription.

View alert

Audit documentation

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