CPT procedure code

81599

Medicare payment

No national Medicare fee schedule we hold prices 81599 — the Physician Fee Schedule lists it with status indicator X (2026 file). CMS fee schedules ↗

Code definition

Code

81599

Code system

CPT (Current Procedural Terminology)

This CPT code is not in our curated reference. CPT codes are maintained by the American Medical Association (AMA). Full descriptions require an AMA license.

Category

Short description sourced from CMS publicly available fee schedule data. Full CPT descriptions are copyright AMA. Not a substitute for the official CPT codebook.

Policy activity for CPT 81599

CLV Intelligence is tracking 40+ policy changes that cite CPT 81599 between 2026-06-05 and 2026-08-27, drawn from 23 LCD/NCD coverage updates, 13 proposed LCDs and 4 MAC LCD revisions. The changes span Clinical Laboratory, Dermatology, Gastroenterology and Multi-specialty, and 5 more. 31 are flagged critical or high priority.

LCD/NCD coverage updates
23
proposed LCDs
13
MAC LCD revisions
4

Counts reflect the source documents CLV has matched to CPT 81599 to date; each links to the government publication that is authoritative. Monitored daily from CMS, the Federal Register, and Medicare Administrative Contractor publications.

Policy changes matched to 81599

Matched to this code by CLV analysis of each policy. The linked source document is authoritative.

LCD L39427: MolDX: Molecular Biomarker Testing to Guide Targeted Therapy Selection in Rheumatoid Arthritis — CGS

Rheumatology · LCD-L39427

Government source· CMS / MACverify ↗
High

Full analysis available with a CLV subscription.

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LCD L39469: MolDX: Molecular Biomarker Testing to Guide Targeted Therapy Selection in Rheumatoid Arthritis — Noridian

Rheumatology · LCD-L39469

Government source· CMS / MACverify ↗
High

Full analysis available with a CLV subscription.

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LCD L36256: MolDX: Molecular Diagnostic Tests (MDT) — Noridian

Clinical Laboratory · LCD-L36256

Government source· CMS / MACverify ↗
High

Full analysis available with a CLV subscription.

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LCD L37750: MolDX: Melanoma Risk Stratification Molecular Testing — Noridian

Oncology · LCD-L37750

Government source· CMS / MACverify ↗
High

Full analysis available with a CLV subscription.

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LCD L38016: MolDX: Melanoma Risk Stratification Molecular Testing — CGS

Dermatology · LCD-L38016

Government source· CMS / MACverify ↗
High

Full analysis available with a CLV subscription.

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LCD L38582: MolDX: Molecular Testing for Solid Organ Allograft Rejection — CGS

Transplantation · LCD-L38582

Government source· CMS / MACverify ↗
High

Full analysis available with a CLV subscription.

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LCD L36021: MolDX: Molecular Diagnostic Tests (MDT) — CGS

Clinical Laboratory · LCD-L36021

Government source· CMS / MACverify ↗
High

Full analysis available with a CLV subscription.

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Proposed LCD DL40429: MolDX: Transcriptional Biomarkers for Therapeutic Decision-Making in Renal Carcinoma — Palmetto GBA

Oncology · LCD-DL40429

Government source· CMS / MACverify ↗
Critical

Full analysis available with a CLV subscription.

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LCD L37725: MolDX: Melanoma Risk Stratification Molecular Testing — Palmetto GBA

Dermatology · LCD-L37725

Government source· CMS / MACverify ↗
High

Full analysis available with a CLV subscription.

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LCD L37748: MolDX: Melanoma Risk Stratification Molecular Testing — Noridian

Oncology · LCD-L37748

Government source· CMS / MACverify ↗
High

Full analysis available with a CLV subscription.

View alert

Audit documentation

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