CMS Transmittal R13804DEMO: Update to GUIDE Model Appendices for July 2026
Multi-specialty
CPT procedure code
Code definition
Code
99221
Code system
CPT (Current Procedural Terminology)
Description
Initial hospital inpatient care, low complexity
Category
E/M
Short description sourced from CMS publicly available fee schedule data. Full CPT descriptions are copyright AMA. Not a substitute for the official CPT codebook.
Latest reimbursement alerts
No alerts currently reference 99221 directly. Here are the latest policy changes across all codes.
Multi-specialty
Physician Fee Schedule
General
General
Physician Fee Schedule
General
Related CPT codes (992xx)
99202E/MOffice/outpatient visit, new patient, low complexity
99203E/MOffice/outpatient visit, new patient, moderate complexity
99204E/MOffice/outpatient visit, new patient, moderate-high complexity
99205E/MOffice/outpatient visit, new patient, high complexity
99211E/MOffice/outpatient visit, established patient, minimal
99212E/MOffice/outpatient visit, established patient, straightforward
99213E/MOffice/outpatient visit, established patient, low complexity
99214E/MOffice/outpatient visit, established patient, moderate complexity
99215E/MOffice/outpatient visit, established patient, high complexity
99222E/MInitial hospital inpatient care, moderate complexity
99223E/MInitial hospital inpatient care, high complexity
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