HCPCS Level II code

G0483Drug test(s), definitive, utilizing (1) drug identification methods able to identify individual drugs and distinguish between structural isomers (but not necessarily stereoisomers), including, but not limited to gc/ms (any type, single or tandem) and lc/ms (any type, single or tandem and excluding immunoassays (e.g., ia, eia, elisa, emit, fpia) and enzymatic methods (e.g., alcohol dehydrogenase)), (2) stable isotope or other universally recognized internal standards in all samples (e.g., to control for matrix effects, interferences and variations in signal strength), and (3) method or drug-specific calibration and matrix-matched quality control material (e.g., to control for instrument variations and mass spectral drift); qualitative or quantitative, all sources, includes specimen validity testing, per day; 22 or more drug class(es), including metabolite(s) if performed

HCPCS Level IIVerified Sep 5, 2026

Medicare payment

$246.92

2026 Clinical Laboratory Fee Schedule

Source: CMS Clinical Laboratory Fee Schedule (2026). CMS fee schedules ↗ · PFS status indicator X

National amount before geographic adjustment. Your MAC's locality rate will differ.

Code definition

Code

G0483

Code system

HCPCS Level II

Full description

Drug test(s), definitive, utilizing (1) drug identification methods able to identify individual drugs and distinguish between structural isomers (but not necessarily stereoisomers), including, but not limited to gc/ms (any type, single or tandem) and lc/ms (any type, single or tandem and excluding immunoassays (e.g., ia, eia, elisa, emit, fpia) and enzymatic methods (e.g., alcohol dehydrogenase)), (2) stable isotope or other universally recognized internal standards in all samples (e.g., to control for matrix effects, interferences and variations in signal strength), and (3) method or drug-specific calibration and matrix-matched quality control material (e.g., to control for instrument variations and mass spectral drift); qualitative or quantitative, all sources, includes specimen validity testing, per day; 22 or more drug class(es), including metabolite(s) if performed

Policy activity for HCPCS G0483

CLV Intelligence is tracking 5 policy changes that cite HCPCS G0483 between 2026-06-05 and 2026-07-23, drawn from 5 LCD/NCD coverage updates. The changes span Clinical Laboratory and Pain Management.

LCD/NCD coverage updates
5

Counts reflect the source documents CLV has matched to HCPCS G0483 to date; each links to the government publication that is authoritative. Monitored daily from CMS, the Federal Register, and Medicare Administrative Contractor publications.

Recent policy changes matched to G0483

Matched to this code by CLV analysis of each policy. The linked source document is authoritative.

LCD L36029: Urine Drug Testing — CGS

Pain Management

Government source· CMS / MACverify ↗
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Audit documentation

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