FDA Approval: HEMANGEOL (PROPRANOLOL HYDROCHLORIDE) — Type 5 - New Formulation or New Manufacturer
Policy FDA-NDA205410 • Cardiology
HighHemangeol (propranolol hydrochloride) is an oral solution approved under NDA205410 as a new formulation for an orphan indication, billing through Medicare Part D as a self-administered oral drug. As a
FDA Approval: LEQVIO (INCLISIRAN) — Type 1 - New Molecular Entity
Policy FDA-NDA214012 • Cardiology
HighLeqvio (inclisiran) is a subcutaneously administered siRNA therapy approved for LDL-C reduction, with a confirmed Part B billing pathway reflecting its physician-office or clinic administration model.
FDA Approval: LEROCHOL (LERODALCIBEP-LIGA) — Type 1 - New Molecular Entity
Policy FDA-BLA761427 • Cardiology
HighLEROCHOL (lerodalcibep-liga), approved December 12, 2025 as a new molecular entity injectable, follows a Part B billing pathway consistent with its injectable route of administration. As a brand-new m
FDA Approval: INPEFA (SOTAGLIFLOZIN) — Type 1 - New Molecular Entity
Policy FDA-NDA216203 • Cardiology
HighInpefa (sotagliflozin) is an oral tablet approved as a new molecular entity, placing it squarely in the Part D billing pathway for Medicare outpatient prescription drug coverage. As an SGLT2 inhibitor
FDA Approval: TRYVIO (APROCITENTAN) — Type 1 - New Molecular Entity
Policy FDA-NDA217686 • Cardiology
HighTryvio (aprocitentan) is an oral endothelin receptor antagonist approved for resistant hypertension, billing through Medicare Part D as a self-administered tablet. As an oral outpatient medication, it
FDA Approval: FUROSCIX (FUROSEMIDE INJECTION 80 MG/ 10 ML) — Type 3 - New Dosage Form
Policy FDA-NDA209988 • Cardiology
HighFuroscix (furosemide 80 mg/10 mL subcutaneous injection) received FDA approval in October 2022 as a new dosage form of furosemide for subcutaneous administration, designated under Part B given its inj
FDA Approval: BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE (BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE) — Type 4 - New Combination
Policy FDA-NDA020186 • Cardiology
RoutineBisoprolol fumarate and hydrochlorothiazide is an oral tablet combination of a beta-blocker and thiazide diuretic approved for hypertension, billing under Medicare Part D as a self-administered oral m
FDA Approval: AVAPRO (IRBESARTAN) — Type 1 - New Molecular Entity
Policy FDA-NDA020757 • Cardiology
RoutineAvapro (irbesartan) is an oral angiotensin II receptor blocker approved for hypertension, billing under Medicare Part D as a self-administered tablet. As a long-genericized oral medication with numero
LCD L33560: Cardiovascular Nuclear Medicine — Wellpoint Federal
Policy LCD-L33560 • Cardiology
HighThis active final LCD (L33560) from Wellpoint Federal governs coverage criteria for cardiovascular nuclear medicine services under both Part A and Part B, effective April 1, 2026. It defines the indic
LCD L33559: Cardiac Computed Tomography (CCT) and Coronary Computed Tomography Angiography (CCTA) — Wellpoint Federal
Policy LCD-L33559 • Cardiology
HighThis active final LCD from Wellpoint Federal governs coverage of Cardiac Computed Tomography (CCT) and Coronary Computed Tomography Angiography (CCTA) under Medicare Part A and Part B, effective April
LCD L39863: Artificial Intelligence Enabled CT Based Quantitative Coronary Topography (AI-QCT)/Coronary Plaque Analysis (AI-CPA) — Wellpoint Federal
Policy LCD-L39863 • Cardiology
HighThis final LCD from Wellpoint Federal (L39863) establishes coverage criteria for AI-enabled CT-based quantitative coronary topography and coronary plaque analysis, effective April 1, 2026. It governs
FDA Approval: ENLICITIDE (ENLICITIDE CHLORIDE) — Type 1 - New Molecular Entity
Policy FDA-NDA220848 • Cardiology
RoutineLIPFENDRA (enlicitide decanoate) is an oral tablet approved via NDA220848, placing it squarely in the Medicare Part D billing pathway rather than Part B. As an oral drug dispensed through retail or sp
LCD L33627: Non-Invasive Vascular Studies — Wellpoint Federal
Policy LCD-L33627 • Cardiology
HighLCD L33627 establishes coverage criteria for non-invasive vascular studies under both Part A and Part B with Wellpoint Federal, effective April 1, 2026. This final, active LCD governs the medical nece
LCD L39075: Non-Invasive Fractional Flow Reserve (FFR) for Ischemic Heart Disease — Wellpoint Federal
Policy LCD-L39075 • Cardiology
HighThis active final LCD from Wellpoint Federal establishes coverage criteria for non-invasive fractional flow reserve (FFR) testing in ischemic heart disease, effective April 1, 2026. It governs when CT
LCD L33623: Percutaneous Coronary Intervention — Wellpoint Federal
Policy LCD-L33623 • Cardiology
HighThis active final LCD from Wellpoint Federal governs coverage criteria for Percutaneous Coronary Intervention (PCI) under Medicare Part A and Part B, effective April 1, 2026. It establishes the clinic
LCD L33577: Transthoracic Echocardiography (TTE) — Wellpoint Federal
Policy LCD-L33577 • Cardiology
HighThis final LCD from Wellpoint Federal governs coverage of Transthoracic Echocardiography (TTE) under Medicare Part A and Part B, effective April 1, 2026. It establishes the indications, limitations, a
LCD L33579: Transesophageal Echocardiography (TEE) — Wellpoint Federal
Policy LCD-L33579 • Cardiology
HighThis active final LCD from Wellpoint Federal governs coverage criteria for Transesophageal Echocardiography (TEE) under both Part A and Part B, effective April 1, 2026. It establishes the indications,
FDA Approval: REPATHA (EVOLOCUMAB) — Type 1 - New Molecular Entity
Policy FDA-BLA125522 • Cardiology
HighRepatha (evolocumab) is a PCSK9 inhibitor approved as an injectable, supporting a Part B billing pathway for physician-administered doses. As a novel biologic at the time of approval, billing teams sh
FDA Approval: ELIQUIS (APIXABAN) — Type 1 - New Molecular Entity
Policy FDA-NDA202155 • Cardiology
RoutineEliquis (apixaban) is an oral anticoagulant approved as a tablet (including a tablet for suspension formulation), which routes it through Medicare Part D for outpatient prescription coverage. As an or
FDA Approval: ELIQUIS (APIXABAN) — Type 3 - New Dosage Form
Policy FDA-NDA220073 • Cardiology
RoutineEliquis (apixaban) has received approval for a new oral suspension dosage form under NDA220073, expanding access for patients unable to swallow tablets—likely pediatric or dysphagic populations. As an
FDA Approval: ARGATROBAN IN SODIUM CHLORIDE (ARGATROBAN) — Type 5 - New Formulation or New Manufacturer
Policy FDA-NDA022434 • Cardiology
HighArgatroban in sodium chloride is an injectable medication that will likely receive a J-code for billing purposes under Medicare Part B. As an intravenous drug, it may also qualify for pass-through pay
LCD L40255: Temporary Nontherapeutic Ambulatory Cardiac Monitoring Devices — Noridian
Policy LCD-L40255 (Notice Ends 06/20/2026) • Cardiology
HighThis final LCD from Noridian (Jurisdictions E and F) establishes coverage criteria for temporary nontherapeutic ambulatory cardiac monitoring devices, effective August 13, 2026, across 15 western stat
LCD L40257: Temporary Nontherapeutic Ambulatory Cardiac Monitoring Devices — Palmetto GBA
Policy LCD-L40257 (Notice Ends 06/27/2026) • Cardiology
HighThis final LCD from Palmetto GBA establishes coverage criteria for temporary nontherapeutic ambulatory cardiac monitoring devices effective June 28, 2026, across seven southeastern states under Part A
LCD L40244: Temporary Nontherapeutic Ambulatory Cardiac Monitoring Devices — CGS
Policy LCD-L40244 (Notice Ends 06/27/2026) • Cardiology
HighThis final LCD from CGS (J15) governs coverage of temporary nontherapeutic ambulatory cardiac monitoring devices in Kentucky and Ohio, effective June 28, 2026. It establishes the indications, document
Proposed LCD DL34410: B-type Natriuretic Peptide (BNP) Testing — Palmetto GBA
Policy LCD-DL34410 • Cardiology
RoutineThe proposed Local Coverage Determination (LCD) for B-type Natriuretic Peptide (BNP) testing may significantly impact billing by clarifying coverage criteria and necessity for the test, potentially im
Proposed LCD DL40244: Temporary Nontherapeutic Ambulatory Cardiac Monitoring Devices — CGS
Policy LCD-DL40244 • Cardiology
RoutineThe proposed LCD for Temporary Nontherapeutic Ambulatory Cardiac Monitoring Devices may impact billing by providing clearer guidelines for reimbursement. This could facilitate appropriate claims submi
Proposed LCD DL40255: Temporary Nontherapeutic Ambulatory Cardiac Monitoring Devices — Noridian
Policy LCD-DL40255 • Cardiology
RoutineThe proposed LCD regarding temporary nontherapeutic ambulatory cardiac monitoring devices may introduce changes in billing practices and reimbursement rates. Providers may need to update their coding
Proposed LCD DL40228: Endovascular Management for Peripheral Arterial Disease of the Upper and Lower Extremities — Palmetto GBA
Policy LCD-DL40228 • Cardiology
RoutineThe proposed LCD for Endovascular Management of Peripheral Arterial Disease will likely supports compliance with updated rates clarity for services related to both upper and lower extremities. This change could lead to incr
Proposed LCD DL40257: Temporary Nontherapeutic Ambulatory Cardiac Monitoring Devices — Palmetto GBA
Policy LCD-DL40257 • Cardiology
RoutineThe proposed LCD may impact billing for nontherapeutic cardiac monitoring devices, potentially leading to increased scrutiny during the claim process. Providers should prepare for possible denials or
LCD L33423: Cardiac Computed Tomography & Angiography (CCTA) — Palmetto GBA
Policy LCD-L33423 • Cardiology
HighThe new LCD by Palmetto GBA regarding Cardiac Computed Tomography and Angiography (CCTA) has significant implications for billing practices. Providers must ensure proper documentation and alignment wi
LCD L39938: MolDX: Genetic Testing for Heritable Thoracic Aortic Disease — CGS
Policy LCD-L39938 • Cardiology
HighThe upcoming LCD on genetic testing for heritable thoracic aortic disease may streamline billing processes for such tests, ensuring better reimbursement for providers. This could lead to increased acc
LCD L39933: MolDX: Genetic Testing for Heritable Thoracic Aortic Disease — Palmetto GBA
Policy LCD-L39933 • Cardiology
HighThe recent MolDX guidelines for genetic testing of heritable thoracic aortic disease by Palmetto GBA may require updates to existing billing practices. Providers will need to ensure compliance with th
LCD L39989: MolDX: Genetic Testing for Heritable Thoracic Aortic Disease — WPS
Policy LCD-L39989 • Cardiology
HighThe new LCD for genetic testing related to heritable thoracic aortic disease may significantly impact billing practices for related tests. Providers should prepare for changes in coding and coverage t
LCD L34551: One Day Stays for Chest Pain — Palmetto GBA
Policy LCD-L34551 • Cardiology
HighThe implementation of this new LCD may affect billing for one-day stays associated with chest pain, potentially resulting in increased scrutiny on documentation and coding. Proper adherence to the gui
LCD L34636: Electrocardiographic (EKG or ECG) Monitoring (Holter or Real-Time Monitoring) — WPS
Policy LCD-L34636 • Cardiology
HighThe introduction of this LCD for EKG Monitoring requires billing team review-time monitoring services. Providers will need to ensure compliance
LCD L38771: Non-Invasive Fractional Flow Reserve (FFR) for Ischemic Heart Disease — CGS
Policy LCD-L38771 • Cardiology
HighThe introduction of non-invasive fractional flow reserve (FFR) for ischemic heart disease will potentially enhance the diagnostic capabilities for cardiology providers. This may lead to increased bill
LCD L34084: Transcatheter Infusion Therapy — CGS
Policy LCD-L34084 • Cardiology
HighThe implementation of the LCD for Transcatheter Infusion Therapy will likely influence billing practices, requiring updates to coding and documentation processes. Providers should prepare for potentia
LCD L34087: Surveillance of Implantable or Wearable Cardioverter Defibrillators (ICDs): Office, Hospital, Web, or Non-Web Based — CGS
Policy LCD-L34087 • Cardiology
HighThe introduction of surveillance requirements for implantable or wearable cardioverter defibrillators (ICDs) could lead to supports compliance with updated rates workload for providers. Ensuring complia
LCD L34337: Transesophageal Echocardiography (TEE) — CGS
Policy LCD-L34337 • Cardiology
HighThe implementation of new Local Coverage Determination (LCD) for Transesophageal Echocardiography (TEE) is expected to streamline billing processes, potentially leading to improved reimbursement rates
LCD L34338: Transthoracic Echocardiography (TTE) — CGS
Policy LCD-L34338 • Cardiology
HighThe introduction of the CGS contract for Transthoracic Echocardiography (TTE) may lead to supports compliance with updated rates practices for echocardiograms. Providers should ensure compliance with the new L
LCD L33947: Cardiac Computed Tomography (CCT) and Coronary Computed Tomography Angiography (CCTA) — CGS
Policy LCD-L33947 • Cardiology
HighThe implementation of the new LCD for Cardiac Computed Tomography and Coronary Angiography may impact billing processes related to these services by establishing specific criteria for reimbursement. P
LCD L39881: Artificial Intelligence Enabled CT Based Quantitative Coronary Topography (AI-QCT )/Coronary Plaque Analysis (AI-CPA) — Noridian
Policy LCD-L39881 • Cardiology
HighThe introduction of AI-QCT and AI-CPA will enhance the diagnostic capabilities in cardiology, potentially leading to supports compliance with updated rates due to improved efficiency in coronary plaque analysis. Pro
LCD L34324: Cardiovascular Stress Testing, Including Exercise and/or Pharmacological Stress and Stress Echocardiography — Noridian
Policy LCD-L34324 • Cardiology
HighThe implementation of the Noridian LCD for Cardiovascular Stress Testing requires billing team review.
LCD L36889: Cardiovascular Stress Testing, Including Exercise and/or Pharmacological Stress and Stress Echocardiography — Noridian
Policy LCD-L36889 • Cardiology
HighThe recent LCD for cardiovascular stress testing emphasizes the necessity for compliance with updated guidelines, which may impact reimbursement. Providers must ensure correct documentation and coding
LCD L39883: Artificial Intelligence Enabled CT Based Quantitative Coronary Topography (AI-QCT )/Coronary Plaque Analysis (AI-CPA) — Noridian
Policy LCD-L39883 • Cardiology
HighThe introduction of AI-QCT and AI-CPA technology will enhance compliance updates for cardiovascular imaging services. This may lead to supports compliance with updated rates for advanced coronary plaque ana
LCD L37379: Echocardiography — Palmetto GBA
Policy LCD-L37379 • Cardiology
HighThe LCD for Echocardiography will impact billing practices starting October 23, 2025. Providers will need to stay updated on specific guidelines and documentation requirements to ensure compliance and
LCD L34761: Percutaneous Coronary Interventions — WPS
Policy LCD-L34761 • Cardiology
HighThe implementation of the new LCD for Percutaneous Coronary Interventions will significantly impact billing practices for cardiovascular procedures. Providers must ensure compliance with the updated g
LCD L35121: Coronary Computed Tomography Angiography (CCTA) — WPS
Policy LCD-L35121 • Cardiology
HighThe implementation of the LCD for Coronary Computed Tomography Angiography (CCTA) may lead to increased scrutiny on claims processing and reimbursement rates. Facilities should prepare for potential c
LCD L35998: Non-Coronary Vascular Stents — WPS
Policy LCD-L35998 • Cardiology
HighThe introduction of non-coronary vascular stents under WPS may lead to updated billing practices. Providers would need to familiarize themselves with the new coding and reimbursement policies to ensur
LCD L34315: Electrocardiograms — Noridian
Policy LCD-L34315 • Cardiology
HighThe new Local Coverage Determination (LCD) for electrocardiograms set to take effect on November 6, 2025, may alter the reimbursement landscape for cardiology practices. Providers should prepare for c