Federal Register Notice: Medicare Program: Public Meeting Regarding New and Reconsidered Clinical Diagnostic Laboratory Test Codes for the Clinical Laboratory Fee Schedule for Calendar Year 2027
Policy FR-2026-08511 • Clinical Laboratory
HighThe upcoming public meeting for the Clinical Laboratory Fee Schedule will focus on new and reconsidered test codes, which could significantly influence payment amounts for laboratories. Stakeholders a
Federal Register Notice: Medicare Program: Public Meeting Regarding New and Reconsidered Clinical Diagnostic Laboratory Test Codes for the Clinical Laboratory Fee Schedule for Calendar Year 2026-June 27, 2025
Policy FR-2025-06756 • Clinical Laboratory
HighThe upcoming public meeting will impact the reimbursement strategies for new and revised clinical diagnostic laboratory test codes under the Clinical Laboratory Fee Schedule (CLFS) for 2026. Stakehold
Federal Register Notice: Public Meeting on June 25, 2024 Regarding New and Reconsidered Clinical Diagnostic Laboratory Test Codes for the Clinical Laboratory Fee Schedule for Calendar Year 2025
Policy FR-2024-08005 • Clinical Laboratory
HighThe upcoming public meeting on June 25, 2024, will address new and reconsidered clinical diagnostic laboratory test codes impacting the Clinical Laboratory Fee Schedule for 2025. Stakeholders will hav
Federal Register Notice: Medicare Program; Public Meeting on June 22, 2023 Regarding New and Reconsidered Clinical Diagnostic Laboratory Test Codes for the Clinical Laboratory Fee Schedule for Calendar Year 2024
Policy FR-2023-07909 • Clinical Laboratory
HighThe public meeting focuses on establishing payment amounts for new and revised laboratory test codes under the Clinical Laboratory Fee Schedule, potentially impacting reimbursement rates for diagnosti
Proposed LCD DL36351: Lab: Special Histochemical Stains and Immunohistochemical Stains — Noridian
Policy LCD-DL36351 • Clinical Laboratory
HighThe proposed local coverage determination (LCD) for histochemical and immunohistochemical stains could impact billing by clarifying guidelines and coverage for these laboratory tests. This may lead to
Proposed LCD DL36353: Lab: Special Histochemical Stains and Immunohistochemical Stains — Noridian
Policy LCD-DL36353 • Clinical Laboratory
HighThe proposed Local Coverage Decision regarding special histochemical and immunohistochemical stains may impact billing practices for laboratories. Providers should ensure that they have appropriate do
Proposed LCD DL40058: MolDX: Molecular Testing for Solid Organ Allograft Rejection — Palmetto GBA
Policy LCD-DL40058 • Clinical Laboratory
HighThe proposed LCD by Palmetto GBA for molecular testing related to solid organ allograft rejection could impact billing significantly by establishing specific criteria for coverage. This may lead to in
Proposed LCD DL40140: MolDX: Molecular Testing for Solid Organ Allograft Rejection — CGS
Policy LCD-DL40140 • Clinical Laboratory
HighThe proposed Local Coverage Determination (LCD) for molecular testing related to solid organ allograft rejection could significantly influence billing practices for relevant tests. With proper coding,
Federal Register Final Rule: Clinical Laboratory Improvement Amendments of 1988 (CLIA) Fees; Histocompatibility, Personnel, and Alternative Sanctions for Certificate of Waiver Laboratories
Policy FR-2023-28170 • Clinical Laboratory
HighThe updated CLIA fees will impact reimbursement for clinical laboratory services, potentially increasing costs for laboratories while ensuring sustainable funding for the program. Enhanced fees for fo
LCD L39935: MolDX: Molecular Testing for Identification and Management of Hereditary Transthyretin Amyloidosis — Palmetto GBA
Policy LCD-L39935 • Clinical Laboratory
HighThe new MolDX coverage for hereditary transthyretin amyloidosis testing will provide reimbursement pathways for diagnostic molecular tests, benefiting patients and providers through enhanced testing a
LCD L34011: Ionized Calcium — First Coast
Policy LCD-L34011 • Clinical Laboratory
HighThe effective date of the LCD for Ionized Calcium indicates changes in the coverage and billing practices for this test. This may lead to adjustments in claims processing and reimbursement rates, requ
LCD L33996: Vitamin D Assay Testing — CGS
Policy LCD-L33996 • Clinical Laboratory
HighThe implementation of the new LCD on Vitamin D Assay Testing will impact billing practices significantly. Providers will need to familiarize themselves with the new guidelines to ensure appropriate re
LCD L36692: Vitamin D Assay Testing — Noridian
Policy LCD-L36692 • Clinical Laboratory
HighThe introduction of the new LCD for Vitamin D Assay Testing by Noridian may affect billing practices, ensuring that healthcare providers follow updated guidelines for testing reimbursement. As a resul
LCD L34051: Vitamin D Assay Testing — Noridian
Policy LCD-L34051 • Clinical Laboratory
HighThe recent LCD regarding Vitamin D assay testing by Noridian may impact billing practices significantly, especially in terms of coverage and reimbursement rates. Providers must ensure compliance with
LCD L36021: MolDX: Molecular Diagnostic Tests (MDT) — CGS
Policy LCD-L36021 • Clinical Laboratory
HighThe introduction of the MolDX: Molecular Diagnostic Tests policy will significantly impact billing practices for molecular diagnostics, potentially leading to changes in reimbursement rates. It is cru
LCD L34658: Vitamin D Assay Testing — WPS
Policy LCD-L34658 • Clinical Laboratory
HighThe LCD on Vitamin D Assay Testing by WPS may impact billing by clarifying coverage criteria which may lead to more denials for tests not meeting the outlined requirements. This could require provider
LCD L37616: Lab: Cystatin C Measurement — Noridian
Policy LCD-L37616 • Clinical Laboratory
HighThe new LCD for Cystatin C Measurement by Noridian, effective September 11, 2025, may impact billing practices for clinical laboratories. Providers will need to ensure compliance with the guidelines o
LCD L36351: Lab: Special Histochemical Stains and Immunohistochemical Stains — Noridian
Policy LCD-L36351 • Clinical Laboratory
HighThe introduction of new guidelines for Special Histochemical and Immunohistochemical Stains by Noridian may impact billing practices significantly. Providers should ensure they are familiar with the n
LCD L36353: Lab: Special Histochemical Stains and Immunohistochemical Stains — Noridian
Policy LCD-L36353 • Clinical Laboratory
HighThe new LCD on Special Histochemical and Immunohistochemical Stains is likely to impact lab billing practices significantly by specifying the criteria for coverage. Providers should ensure that their
LCD L37618: Lab: Cystatin C Measurement — Noridian
Policy LCD-L37618 • Clinical Laboratory
HighThe upcoming Local Coverage Determination for Cystatin C Measurement may impact billing practices significantly as of its effective date in February 2025. Providers will need to ensure they understand
LCD L38294: MolDX: Pharmacogenomics Testing — Palmetto GBA
Policy LCD-L38294 • Clinical Laboratory
HighThe introduction of the MolDX Pharmacogenomics Testing LCD by Palmetto GBA may significantly impact the billing for genetic testing services within the specified effective date. Providers must ensure
LCD L38435: MolDX: Pharmacogenomics Testing — WPS
Policy LCD-L38435 • Clinical Laboratory
HighThe new LCD for Pharmacogenomics Testing by WPS may lead to supports compliance with updated rates practices for these tests. Providers will need to ensure that they meet the updated criteria to avoid claim de
LCD L37066: Lab: Coenzyme Q10 (CoQ10) — Noridian
Policy LCD-L37066 • Clinical Laboratory
HighThe addition of coverage for Coenzyme Q10 (CoQ10) may lead to increased lab compliance updates for outpatient labs. Proper coding and documentation are essential to ensure reimbursement and complia
LCD L36702: Serum Magnesium — Noridian
Policy LCD-L36702 • Clinical Laboratory
HighThe new LCD for Serum Magnesium by Noridian could impact billing by necessitating updated coding practices and justification for claims related to serum magnesium levels. Providers should prepare for
LCD L37620: MDS FISH — Noridian
Policy LCD-L37620 • Clinical Laboratory
HighThe introduction of the MDS FISH LCD by Noridian is expected to impact billing processes significantly starting from the effective date of October 23, 2025. Providers will need to familiarize themselv
LCD L36700: Serum Magnesium — Noridian
Policy LCD-L36700 • Clinical Laboratory
HighThe LCD for Serum Magnesium under Noridian may lead to changes in reimbursement for associated tests. Practitioners should ensure compliance with the new guidelines to avoid revenue impact.
LCD L37068: Lab: Coenzyme Q10 (CoQ10) — Noridian
Policy LCD-L37068 • Clinical Laboratory
HighThe addition of Coenzyme Q10 (CoQ10) to the lab test offerings under Noridian could enhance compliance updates for clinicians addressing certain conditions where CoQ10 is indicated. Providers shoul
LCD L38394: MolDX: Pharmacogenomics Testing — CGS
Policy LCD-L38394 • Clinical Laboratory
HighThe introduction of MolDX: Pharmacogenomics Testing will significantly impact billing processes starting October 23, 2025. Providers must stay updated on the specific coding and coverage criteria to e
LCD L37622: MDS FISH — Noridian
Policy LCD-L37622 • Clinical Laboratory
HighThe introduction of the MDS FISH LCD by Noridian may affect billing processes, particularly for laboratories performing MDS-related testing. Providers should familiarize themselves with the specific r
LCD L37062: BDX-XL2 — Noridian
Policy LCD-L37062 • Clinical Laboratory
HighThe implementation of LCD BDX-XL2 by Noridian may require changes in billing practices for affected services. Providers need to ensure they are coding accurately to comply with the new coverage guidel
LCD L34215: Lab: Flow Cytometry — Noridian
Policy LCD-L34215 • Clinical Laboratory
HighThe new LCD for Flow Cytometry by Noridian, effective from 11/06/2025, may affect billing practices by requiring specific documentation and justification for tests performed. Providers will need to st
LCD L36094: Lab: Flow Cytometry — Noridian
Policy LCD-L36094 • Clinical Laboratory
HighThe implementation of the LCD for Flow Cytometry by Noridian may significantly affect billing practices for laboratories. Providers must ensure that they are accurately coding and documenting services
LCD L37598: Cystatin C Measurement — CGS
Policy LCD-L37598 • Clinical Laboratory
HighThe introduction of Cystatin C Measurement coverage could potentially supports compliance with updated rates for laboratories offering this test, impacting overall billing processes among providers. It may encou
LCD L37602: MDS FISH — Palmetto GBA
Policy LCD-L37602 • Clinical Laboratory
HighThe implementation of the MDS FISH LCD by Palmetto GBA may affect reimbursement levels for certain diagnostic tests, potentially impacting overall billing practices. Providers should prepare for chang
LCD L39391: Vitamin D Assay Testing — Palmetto GBA
Policy LCD-L39391 • Clinical Laboratory
HighThe new LCD for Vitamin D assay testing enacted by Palmetto GBA may impact billing processes for providers. They should prepare to implement updated codes and guidelines on or after the effective date
LCD L37608: MDS FISH — CGS
Policy LCD-L37608 • Clinical Laboratory
HighThe new LCD for MDS FISH from CGS may impact billing for genetic testing services. Providers will need to familiarize themselves with the updated guidelines to ensure compliance and appropriate reimbu
LCD L35160: MolDX: Molecular Diagnostic Tests (MDT) — Noridian
Policy LCD-L35160 • Clinical Laboratory
HighThe new MolDX coverage by Noridian will impact billing for molecular diagnostic tests significantly. Starting from February 2026, providers must ensure compliance with the updated guidelines to maximi
LCD L39950: MolDX: Molecular Testing for Identification and Management of Hereditary Transthyretin Amyloidosis — Noridian
Policy LCD-L39950 • Clinical Laboratory
HighThe implementation of the MolDX for hereditary transthyretin amyloidosis will have significant implications for billing processes, particularly in the realm of genetic testing reimbursements. Faciliti
LCD L38353: MolDX: Repeat Germline Testing — Noridian
Policy LCD-L38353 • Clinical Laboratory
HighThe new LCD from Noridian regarding repeat germline testing may necessitate adjustments in billing practices to ensure compliance with updated coverage guidelines. Providers should assess their existi
LCD L36256: MolDX: Molecular Diagnostic Tests (MDT) — Noridian
Policy LCD-L36256 • Clinical Laboratory
HighThe implementation of the MolDX policy by Noridian allows for the coverage of additional molecular diagnostic tests, which may enhance patient care but can also introduce complexity in billing. Provid
LCD L38070: MolDX: Next-Generation Sequencing Lab-Developed Tests for Myeloid Malignancies and Suspected Myeloid Malignancies — CGS
Policy LCD-L38070 • Clinical Laboratory
HighThe implementation of the MolDX LCD on Next-Generation Sequencing for myeloid malignancies requires billing team review-developed tests. This change is expected to improve reimbursemen
LCD L38335: MolDX: Pharmacogenomics Testing — Noridian
Policy LCD-L38335 • Clinical Laboratory
HighThe implementation of the MolDX: Pharmacogenomics Testing LCD is set to impact billing practices significantly, requiring healthcare providers to adapt to new coverage and documentation requirements.
LCD L35986: Special Histochemical Stains and Immunohistochemical Stains — CGS
Policy LCD-L35986 • Clinical Laboratory
HighThe updated Local Coverage Determination (LCD) on special histochemical and immunohistochemical stains may impact billing practices by outlining specific coding and documentation requirements. Provide
LCD L34037: Flow Cytometry — CGS
Policy LCD-L34037 • Clinical Laboratory
HighThe implementation of the Flow Cytometry LCD by CGS has implications for billing practices starting March 5, 2026. Providers will need to ensure they are compliant with the new guidelines to avoid cla
LCD L38337: MolDX: Pharmacogenomics Testing — Noridian
Policy LCD-L38337 • Clinical Laboratory
HighThe introduction of the MolDX coverage for pharmacogenomics testing could significantly impact billing practices, especially for laboratories that offer genetic testing services. Providers will need t
LCD L39940: MolDX: Molecular Testing for Identification and Management of Hereditary Transthyretin Amyloidosis — CGS
Policy LCD-L39940 • Clinical Laboratory
HighThe new LCD for hereditary transthyretin amyloidosis will have a significant impact on billing practices for laboratories performing molecular testing. Providers will need to ensure they are compliant
LCD L36805: Lab: Special Histochemical Stains and Immunohistochemical Stains — WPS
Policy LCD-L36805 • Clinical Laboratory
HighThe final LCD L36805 details coverage guidelines for special histochemical and immunohistochemical stains, effective April 30, 2026. Providers in the specified states should review this LCD to ensure
LCD L35000: Molecular Pathology Procedures — NGS
Policy LCD-L35000 (Notice Ends 07/14/2026) • Clinical Laboratory
CriticalThe final LCD L35000 focuses on Molecular Pathology Procedures and is set to take effect on July 15, 2026. Providers in relevant states should prepare for potential billing changes associated with thi
CMS Transmittal R13807CP: July 2026 Quarterly Update to the Clinical Laboratory Fee Schedule (CLFS) and Clinical…
Policy CMS-T-R13807CP • Clinical Laboratory
CriticalThe July 2026 Quarterly Update to the Clinical Laboratory Fee Schedule (CLFS) introduces changes that may affect the billing procedures for clinical laboratory services. Billing teams need to review t
2026 Clinical Laboratory Fee Schedule
Policy CLINICAL-LABORATORY-FEE-SCHEDULE-2026 • Clinical Laboratory
High2026 Clinical Laboratory Fee Schedule — official CMS fee schedule. Effective January 1, 2026.