LCD L38680: MolDx: Molecular Testing for Solid Organ Allograft Rejection — WPS
Policy LCD-L38680 • Clinical Laboratory
CriticalThis final LCD from WPS (J5/J8) governs molecular testing for solid organ allograft rejection and is now retired as of its last update, meaning coverage policies under L38680 are no longer active for
LCD L40274: MolDX: Genetic Testing for Hereditary Thrombophilia — WPS
Policy LCD-L40274 • Clinical Laboratory
CriticalThis final LCD from WPS (J5/J8) establishes coverage criteria for genetic testing related to hereditary thrombophilia, effective October 12, 2026, across six Midwestern states. Providers should review
LCD L39911: Total Joint Arthroplasty — WPS
Policy LCD-L39911 • Orthopedics
HighThis final LCD from WPS (J5/J8) establishes coverage criteria for Total Joint Arthroplasty across six Midwestern states, effective August 27, 2026. It governs both Part A and Part B billing, meaning i
LCD L39051: Cosmetic and Reconstructive Surgery — WPS
Policy LCD-L39051 • Multi-specialty
HighThis final LCD from WPS (J5/J8) governs coverage criteria for cosmetic versus reconstructive surgery across Iowa, Missouri, Kansas, Nebraska, Indiana, and Michigan, effective August 27, 2026. It estab
LCD L39907: Micro-Invasive Glaucoma Surgery (MIGS) — WPS
Policy LCD-L39907 • Ophthalmology
HighThis final LCD from WPS (J5/J8) establishes coverage criteria for Micro-Invasive Glaucoma Surgery (MIGS) across six Midwestern states, effective August 27, 2026. It will govern which MIGS procedures a
LCD L34614: Colonoscopy and Sigmoidoscopy-Diagnostic — WPS
Policy LCD-L34614 • Gastroenterology
HighThis active final LCD from WPS (J5/J8) governs coverage criteria for diagnostic colonoscopy and sigmoidoscopy procedures across six Midwestern states, effective August 27, 2026. Providers must ensure
LCD L40278: MolDX: Non-Next Generation Sequencing Targeted Molecular Panel Tests for Targeted Therapy in Cancer — WPS
Policy LCD-L40278 • Oncology
CriticalThis final LCD from WPS (J5/J8) establishes coverage criteria for non-next generation sequencing targeted molecular panel tests used to guide targeted therapy decisions in cancer patients, effective O
LCD L40341: Allergy Diagnostic Testing — WPS
Policy LCD-L40341 • Multi-specialty
CriticalThis final LCD from WPS (J5/J8) establishes coverage criteria for allergy diagnostic testing across six Midwestern states, effective September 27, 2026. Providers performing allergy testing must ensur
LCD L39905: Cataract Surgery — WPS
Policy LCD-L39905 • Ophthalmology
HighThis final LCD from WPS (Jurisdictions 5 and 8) establishes coverage criteria for cataract surgery across six Midwestern states, effective July 30, 2026. It governs both Part A and Part B billing, mea
LCD L38213: Percutaneous Vertebral Augmentation (PVA) for Vertebral Compression Fracture (VCF) — WPS
Policy LCD-L38213 • Orthopedics
HighThis active Final LCD from WPS (J5/J8) establishes coverage criteria for Percutaneous Vertebral Augmentation (PVA) procedures—including vertebroplasty and kyphoplasty—for vertebral compression fractur
LCD L34659: Endoscopic Treatment of GERD — WPS
Policy LCD-L34659 • Gastroenterology
HighThis final LCD from WPS (J5, J8) establishes coverage criteria for endoscopic treatment of GERD, effective July 30, 2026, across six Midwestern states under both Part A and Part B. Providers must ensu
LCD L40249: MolDX: Molecular Testing for Solid Organ Allograft Rejection — WPS
Policy LCD-L40249 • Clinical Laboratory
HighThis final LCD from WPS (J5/J8) establishes coverage criteria for molecular testing used to detect solid organ allograft rejection, effective August 30, 2026. It applies to Medicare Part A and Part B
LCD L39044: MolDX: Molecular Syndromic Panels for Infectious Disease Pathogen Identification Testing — WPS
Policy LCD-L39044 • Infectious Disease / Microbiology
HighThe LCD L39044 focuses on coverage for molecular syndromic panels for infectious disease pathogen identification. As a final LCD, it is currently active and will be effective starting June 25, 2026, i
LCD L39711: MolDX: Molecular Biomarkers for Risk Stratification of Indeterminate Pulmonary Nodules Following Bronchoscopy — WPS
Policy LCD-L39711 • Pulmonology
HighThe finalized LCD L39711 pertains to the use of molecular biomarkers for risk stratification of indeterminate pulmonary nodules following bronchoscopy. This LCD is active and will be effective startin
LCD L40272 (Notice Ends 08/09/2026): MolDX: Biomarker Testing in Metabolic Dysfunction-Associated Steatotic Liver Disease and Metabolic Dysfunction-Associated Steatohepatitis — WPS
Policy LCD-L40272 • Clinical Laboratory
HighLCD L40272 establishes coverage criteria for MolDX biomarker testing in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) and Metabolic Dysfunction-Associated Steatohepatitis (MASH), ef
Proposed LCD DL40022: MolDX: Non-Next Generation Sequencing Tests for the Diagnosis of BCR-ABL Negative Myeloproliferative Neoplasms — WPS
Policy LCD-DL40022 • Hematology
RoutineThe proposed LCD could significantly impact billing practices for non-next generation sequencing tests used in diagnosing BCR-ABL negative myeloproliferative neoplasms. It may lead to a more stringent
Proposed LCD DL40193: Superficial Radiation Therapy (SRT) for the Treatment of Nonmelanoma Skin Cancers (NMSC) — WPS
Policy LCD-DL40193 • Dermatology
RoutineThe proposed LCD for Superficial Radiation Therapy (SRT) will likely supports compliance with updated rates options for providers treating Nonmelanoma Skin Cancers (NMSC). This inclusion may lead to increased utilizat
Proposed LCD DL38682: Transurethral Waterjet Ablation of the Prostate — WPS
Policy LCD-DL38682 • Urology
RoutineThe proposed LCD for Transurethral Waterjet Ablation of the Prostate could potentially impact billing for urologic procedures by establishing coverage criteria and reimbursement rates. It may streamli
Proposed LCD DL36408: Allergen Immunotherapy (AIT) with Subcutaneous Immunotherapy (SCIT) — WPS
Policy LCD-DL36408 • Allergy/Immunology
RoutineThe proposed Local Coverage Determination (LCD) for Allergen Immunotherapy with Subcutaneous Immunotherapy requires billing team review, particularly in allergy-focused practices
Proposed LCD DL40249: MolDX: Molecular Testing for Solid Organ Allograft Rejection — WPS
Policy LCD-DL40249 • Transplantation
RoutineThe proposed LCD on molecular testing for solid organ allograft rejection could significantly affect billing practices by defining specific guidelines for necessary tests and circumstances under which
Proposed LCD DL40251: MolDX: Biomarker Testing for Risk Stratification in DCIS — WPS
Policy LCD-DL40251 • Oncology
RoutineThe proposed LCD could significantly impact billing for biomarker testing in patients with Ductal Carcinoma In Situ (DCIS). Practices may need to adjust their coding and documentation to align with ne
Proposed LCD DL40272: MolDX: Biomarker Testing for Risk Stratification in Metabolic Dysfunction-Associated Steatotic Liver Disease and Metabolic Dysfunction-Associated Steatohepatitis — WPS
Policy LCD-DL40272 • Gastroenterology
RoutineThe proposed LCD for biomarker testing in metabolic liver disease may affect reimbursement practices by clarifying coverage policies which could lead to increased utilization of these tests. Providers
Proposed LCD DL40274: MolDX: Genetic Testing for Hereditary Thrombophilia — WPS
Policy LCD-DL40274 • Hematology
RoutineThe proposed LCD on genetic testing for hereditary thrombophilia could lead to enhanced coverage for specific tests, impacting the way providers bill for related services. This may increase the number
Proposed LCD DL40278: MolDX: Non-Next Generation Sequencing Targeted Molecular Panel Tests for Predictive Testing in Cancer — WPS
Policy LCD-DL40278 • Oncology
RoutineThe proposed Local Coverage Determination (LCD) could significantly affect billing practices for non-next generation sequencing targeted molecular panel tests used in cancer predictive testing. It is
Proposed LCD DL40300: Peripheral Nerve Blocks and Procedures for Chronic Pain — WPS
Policy LCD-DL40300 • Pain Management
RoutineThe proposed LCD on Peripheral Nerve Blocks and Procedures for Chronic Pain may enhance access to necessary pain management techniques, impacting reimbursement for such procedures. The clarity provide
Proposed LCD DL40341: Allergy Diagnostic Testing — WPS
Policy LCD-DL40341 • Allergy/Immunology
RoutineThe proposed LCD for Allergy Diagnostic Testing could impact billing practices by clarifying coverage expectations and potentially enhancing reimbursement rates for providers. As the guidelines are es
Proposed LCD DL40343: Computed Tomography Cerebral Perfusion Analysis (CTP) — WPS
Policy LCD-DL40343 • Radiology
RoutineThe proposed Local Coverage Determination (LCD) for Computed Tomography Cerebral Perfusion Analysis (CTP) requires billing team review. This could increase
Proposed LCD DL39909: Botulinum Toxin Injections — WPS
Policy LCD-DL39909 • Pain Management
RoutineThe proposed LCD for Botulinum Toxin Injections could streamline billing practices, potentially increasing reimbursement rates for providers. It may also clarify guidelines for coverage, leading to re
LCD L34760: Scanning Computerized Ophthalmic Diagnostic Imaging (SCODI) — WPS
Policy LCD-L34760 • Ophthalmology
HighThe new LCD on SCODI by WPS introduces specific guidelines that could impact the billing processes for ophthalmic diagnostic imaging services. Practices may need to adjust their coding and ensure comp
LCD L39987: MolDX: Molecular Testing for Identification and Management of Hereditary Transthyretin Amyloidosis — WPS
Policy LCD-L39987 • Neurology
HighThe implementation of the LCD for molecular testing in hereditary transthyretin amyloidosis requires billing team review. Providers should be aware of the guide
LCD L39989: MolDX: Genetic Testing for Heritable Thoracic Aortic Disease — WPS
Policy LCD-L39989 • Cardiology
HighThe new LCD for genetic testing related to heritable thoracic aortic disease may significantly impact billing practices for related tests. Providers should prepare for changes in coding and coverage t
LCD L40022: MolDX: Non-Next Generation Sequencing Tests for the Diagnosis of BCR-ABL Negative Myeloproliferative Neoplasms — WPS
Policy LCD-L40022 • Hematology
HighWith the new LCD regarding non-next generation sequencing tests for diagnosing BCR-ABL negative myeloproliferative neoplasms effective from August 17, 2025, providers must ensure adjustments are made
LCD L36400: MolDX: Genetic Testing for Hypercoagulability/Thrombophilia (Factor V Leiden, Factor II Prothrombin, and MTHFR) — WPS
Policy LCD-L36400 • Hematology
HighThe implementation of this new LCD on genetic testing for hypercoagulability may create billing complexities for providers. It emphasizes the need for proper documentation and ICD-10 coding to ensure
LCD L36797: MolDX: NRAS Genetic Testing — WPS
Policy LCD-L36797 • Oncology
HighThe upcoming implementation of the NRAS Genetic Testing LCD by WPS will significantly influence billing procedures for oncology-related services. Providers should anticipate changes in claims submissi
LCD L38678: MolDX: Phenotypic Biomarker Detection from Circulating Tumor Cells — WPS
Policy LCD-L38678 • Oncology
HighThe implementation of the MolDX LCD for phenotypic biomarker detection from circulating tumor cells will create significant changes in how tests are reimbursed under Medicare. Providers will need to p
LCD L39481: MolDX: Molecular Biomarker Testing to Guide Targeted Therapy Selection in Rheumatoid Arthritis — WPS
Policy LCD-L39481 • Rheumatology
HighThe implementation of the MolDX guidelines for molecular biomarker testing in rheumatoid arthritis could significantly affect billing processes related to targeted therapy. Providers will need to ensu
LCD L36815: MolDX: Genetic Testing for BCR-ABL Negative Myeloproliferative Disease — WPS
Policy LCD-L36815 • Hematology
HighThe new LCD for genetic testing related to BCR-ABL negative myeloproliferative disease will clarify billing procedures and permissible tests. It is crucial for claims to align with the specified crite
LCD L34645: Urine Drug Testing — WPS
Policy LCD-L34645 • Pain Management
HighThe updated LCD for Urine Drug Testing by WPS may impact reimbursement rates and billing practices for providers. It requires careful review to ensure compliance with new guidelines and proper coding
LCD L37015: Visual Electrophysiology Testing — WPS
Policy LCD-L37015 • Ophthalmology
HighThe new Local Coverage Determination (LCD) for Visual Electrophysiology Testing issued by WPS is expected to impact billing practices significantly starting from August 28, 2025. This may lead to clai
LCD L34658: Vitamin D Assay Testing — WPS
Policy LCD-L34658 • Clinical Laboratory
HighThe LCD on Vitamin D Assay Testing by WPS may impact billing by clarifying coverage criteria which may lead to more denials for tests not meeting the outlined requirements. This could require provider
LCD L34636: Electrocardiographic (EKG or ECG) Monitoring (Holter or Real-Time Monitoring) — WPS
Policy LCD-L34636 • Cardiology
HighThe introduction of this LCD for EKG Monitoring requires billing team review-time monitoring services. Providers will need to ensure compliance
LCD L34536: Treatment of Varicose Veins of the Lower Extremities — WPS
Policy LCD-L34536 • Vascular
HighThe new LCD for the treatment of varicose veins will impact billing by providing clear guidelines and criteria for reimbursement. Providers should prepare for potential changes in claim approvals star
LCD L34624: Somatosensory Testing — WPS
Policy LCD-L34624 • Neurology
HighThe new LCD for Somatosensory Testing establishes specific guidelines that may affect reimbursement rates for this service. Providers will need to ensure they meet the outlined criteria to secure prop
LCD L36408: Allergen Immunotherapy (AIT) with Subcutaneous Immunotherapy (SCIT) — WPS
Policy LCD-L36408 • Allergy/Immunology
HighThe implementation of Allergen Immunotherapy with SCIT may affect billing practices for allergists and related specialists. Providers will need to adjust their coding and documentation to align with n
LCD L39624: Amniotic and Placental Derived Product Injections and/or Applications for Musculoskeletal Indications, Non-Wound — WPS
Policy LCD-L39624 • Pain Management
HighThe new LCD for Amniotic and Placental Derived Product Injections will impact billing practices for musculoskeletal treatments starting September 25, 2025. Providers should prepare for potential chang
LCD L35486: Pelvic Floor Dysfunction: Anorectal Manometry and EMG — WPS
Policy LCD-L35486 • Gastroenterology
HighThe new LCD on Pelvic Floor Dysfunction could significantly affect billing practices for anorectal manometry and EMG procedures. Ensuring compliance with the latest guidelines from WPS will be crucial
LCD L37001: MolDX: MGMT Promoter Methylation Analysis — WPS
Policy LCD-L37001 • Oncology
HighThe implementation of the MGMT Promoter Methylation Analysis LCD requires billing team review. Additionally, this L
LCD L38686: Implantable Continuous Glucose Monitors (I-CGM) — WPS
Policy LCD-L38686 • Endocrinology
HighThe implementation of the new LCD for Implantable Continuous Glucose Monitors (I-CGM) by WPS may affect billing processes for diabetes management services. Providers will need to familiarize themselve
LCD L38435: MolDX: Pharmacogenomics Testing — WPS
Policy LCD-L38435 • Clinical Laboratory
HighThe new LCD for Pharmacogenomics Testing by WPS may lead to supports compliance with updated rates practices for these tests. Providers will need to ensure that they meet the updated criteria to avoid claim de
LCD L38682: Transurethral Waterjet Ablation of the Prostate — WPS
Policy LCD-L38682 • Urology
HighThe introduction of the LCD for Transurethral Waterjet Ablation of the Prostate may lead to increased compliance updates for practices adopting this technology. As coverage becomes effective in Dec