CMS Transmittal R13945MPI: Updates to Chapter 3, Chapter 4, and Chapter 5 in Publication (Pub.) 100-15, Including Updates…
Medicaid
CPT procedure code
88230 — Tissue culture for neoplastic disorders, lymphocyte
PathologyCPT
Medicare payment
$116.49
2026 Clinical Laboratory Fee Schedule
Source: CMS Clinical Laboratory Fee Schedule (2026). CMS fee schedules ↗ · PFS status indicator X
National amount before geographic adjustment. Your MAC's locality rate will differ.
Code definition
Code
88230
Code system
CPT (Current Procedural Terminology)
Description
Tissue culture for neoplastic disorders, lymphocyte
Category
Pathology
Short description sourced from CMS publicly available fee schedule data. Full CPT descriptions are copyright AMA. Not a substitute for the official CPT codebook.
Latest reimbursement alerts
No policy changes are currently matched to 88230. Here are the latest changes across all codes.
High
FDA Approval: RASONQUE (DARAXONRASIB) — Type 1 - New Molecular Entity
Oncology
FDA Approval: VOBRIG (LEUPROLIDE ACETATE) — Type 5 - New Formulation or New Manufacturer
Oncology
FDA Approval: NDA 220106 — Type 1 - New Molecular Entity
Multi-specialty
FDA Approval: BIXLENVO (BICTEGRAVIR/LENACAPAVIR) — Type 4 - New Combination
Infectious Disease
FDA Approval: NDA 221443 — Type 4 - New Combination
Multi-specialty
Audit documentation
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Related CPT codes (882xx)
88233PathologyTissue culture for neoplastic disorders, skin/tissue biopsy
88237PathologyTissue culture for neoplastic disorders, bone marrow/blood
88262PathologyChromosome analysis; 15-20 cells, 2 karyotypes
88271PathologyMolecular cytogenetics; DNA probe, each
88280PathologyChromosome analysis; additional karyotypes, each study
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