88271 — Molecular cytogenetics; DNA probe, each

Medicare payment

$21.42

2026 Clinical Laboratory Fee Schedule

Source: CMS Clinical Laboratory Fee Schedule (2026). CMS fee schedules ↗ · PFS status indicator X

National amount before geographic adjustment. Your MAC's locality rate will differ.

Code definition

Short description sourced from CMS publicly available fee schedule data. Full CPT descriptions are copyright AMA. Not a substitute for the official CPT codebook.

Policy activity for CPT 88271

CLV Intelligence is tracking 6 policy changes that cite CPT 88271 between 2026-06-05 and 2026-08-27, drawn from 4 LCD/NCD coverage updates and 2 proposed LCDs. The changes span Clinical Laboratory and Oncology. 2 are flagged critical or high priority.

LCD/NCD coverage updates

4

proposed LCDs

2

Counts reflect the source documents CLV has matched to CPT 88271 to date; each links to the government publication that is authoritative. Monitored daily from CMS, the Federal Register, and Medicare Administrative Contractor publications.

Policy changes matched to 88271

Matched to this code by CLV analysis of each policy. The linked source document is authoritative.

Related CPT codes (882xx)

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