CMS Transmittal R13945MPI: Updates to Chapter 3, Chapter 4, and Chapter 5 in Publication (Pub.) 100-15, Including Updates…
Medicaid
CPT procedure code
88233 — Tissue culture for neoplastic disorders, skin/tissue biopsy
PathologyCPT
Medicare payment
$140.73
2026 Clinical Laboratory Fee Schedule
Source: CMS Clinical Laboratory Fee Schedule (2026). CMS fee schedules ↗ · PFS status indicator X
National amount before geographic adjustment. Your MAC's locality rate will differ.
Code definition
Code
88233
Code system
CPT (Current Procedural Terminology)
Description
Tissue culture for neoplastic disorders, skin/tissue biopsy
Category
Pathology
Short description sourced from CMS publicly available fee schedule data. Full CPT descriptions are copyright AMA. Not a substitute for the official CPT codebook.
Latest reimbursement alerts
No policy changes are currently matched to 88233. Here are the latest changes across all codes.
High
FDA Approval: RASONQUE (DARAXONRASIB) — Type 1 - New Molecular Entity
Oncology
FDA Approval: VOBRIG (LEUPROLIDE ACETATE) — Type 5 - New Formulation or New Manufacturer
Oncology
FDA Approval: NDA 220106 — Type 1 - New Molecular Entity
Multi-specialty
FDA Approval: BIXLENVO (BICTEGRAVIR/LENACAPAVIR) — Type 4 - New Combination
Infectious Disease
FDA Approval: NDA 221443 — Type 4 - New Combination
Multi-specialty
Audit documentation
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Related CPT codes (882xx)
88230PathologyTissue culture for neoplastic disorders, lymphocyte
88237PathologyTissue culture for neoplastic disorders, bone marrow/blood
88262PathologyChromosome analysis; 15-20 cells, 2 karyotypes
88271PathologyMolecular cytogenetics; DNA probe, each
88280PathologyChromosome analysis; additional karyotypes, each study
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