LCD L36386: MolDX: Breast Cancer Assay: Prosigna® — Noridian
LCD-L36386Oncology · Jun 5, 2026
Government source· CMS / MACverify ↗Full analysis and action recommendations available with a CLV subscription.
ICD-10-CM · CMS Reimbursement Intelligence
Category: C50 · Malignant neoplasm of nipple and areola, right female breast · Verified:
Active alerts
1
CMS Coverage Database
Critical / High
—
Priority signals
Recoverable revenue
$11,820
Conservative annual est.
Sources monitored
7 MAC contractors
Full coverage + CMS
ICD-10-CM Code
C50.419
Code System
ICD-10-CM FY2026
CDC + CMS adopted
Billing status
Billable diagnosis code
Valid for Medicare claim submission
Full clinical description
Malignant neoplasm of upper-outer quadrant of unspecified female breast
Malignant neoplasm of breast falls under Chapter II — Neoplasms. High-priority CMS monitoring for screening, surgical, and oncology treatment coverage policies.
Source: CDC ICD-10-CM Tabular List · CMS National Coverage Analysis
Coverage check · verified
The LCDs whose CMS Billing & Coding article lists C50.419as covered or non-covered — each jurisdiction, effective-dated, linked to the government document. No guesses; if a policy isn’t on file we say so.
See the per-MAC coverage crosswalk for C50.419 — free.
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Local Coverage Determinations (LCDs) from Medicare Administrative Contractors may impose medical necessity requirements for services billed with C50.419. Coverage criteria vary by MAC jurisdiction. Every contractor publishes its LCDs to the CMS Medicare Coverage Database, and CLV Intelligence tracks that database daily for LCD updates affecting this code and related codes.
1 policy change matched to C50.419
Matched by CLV analysis of each policy; the linked source document is authoritative.
LCD-L36386Oncology · Jun 5, 2026
Government source· CMS / MACverify ↗Full analysis and action recommendations available with a CLV subscription.
All seven Medicare Administrative Contractors (MACs) are monitored daily for LCD revisions, billing guidance, and coverage policy updates affecting ICD-10-CM C50.419.
Noridian
JE · JF
Alaska, Arizona, California, Hawaii, Idaho, Montana, Nevada, North Dakota, Oregon, South Dakota, Utah, Washington, Wyoming
CGS
J15
Kentucky, Ohio
Palmetto GBA
JJ · JM
North Carolina, South Carolina, Virginia, West Virginia + Georgia, Tennessee
NGS
J6 · JK
Illinois, Minnesota, Wisconsin + Connecticut, Maine, Massachusetts, New Hampshire, New York, Rhode Island, Vermont
WPS
J5 · J8
Iowa, Kansas, Missouri, Nebraska + Indiana, Michigan
First Coast
JN
Florida, Puerto Rico, U.S. Virgin Islands
Novitas
JH · JL
Arkansas, Colorado, Louisiana, Mississippi, New Mexico, Oklahoma, Texas + Delaware, D.C., Maryland, New Jersey, Pennsylvania
Search C50.419 across the full alert archive
Every CMS transmittal, MAC LCD, and Federal Register notice matched to this code.
Audit documentation
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