Routine
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View alertCPT procedure code
88291
Medicare payment
$33.07
2026 Physician Fee Schedule · non-facility
Source: CMS Physician Fee Schedule (PPRRVU 2026). CMS fee schedules ↗ · PFS status indicator A
National amount before geographic adjustment. Your MAC's locality rate will differ.
Code definition
Code
88291
Code system
CPT (Current Procedural Terminology)
This CPT code is not in our curated reference. CPT codes are maintained by the American Medical Association (AMA). Full descriptions require an AMA license.
Category
—
Short description sourced from CMS publicly available fee schedule data. Full CPT descriptions are copyright AMA. Not a substitute for the official CPT codebook.
Policy activity for CPT 88291
CLV Intelligence is tracking 4 policy changes that cite CPT 88291 most recently on 2026-06-05, drawn from 4 LCD/NCD coverage updates. The changes span Clinical Laboratory.
- LCD/NCD coverage updates
- 4
Counts reflect the source documents CLV has matched to CPT 88291 to date; each links to the government publication that is authoritative. Monitored daily from CMS, the Federal Register, and Medicare Administrative Contractor publications.
Policy changes matched to 88291
Matched to this code by CLV analysis of each policy. The linked source document is authoritative.
Routine
Full analysis available with a CLV subscription.
View alertRoutine
Full analysis available with a CLV subscription.
View alertLCD L37602: MDS FISH — Palmetto GBA
Clinical Laboratory · LCD-L37602
Government source· CMS / MACverify ↗Full analysis available with a CLV subscription.
View alertAudit documentation
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Related CPT codes (882xx)
88230PathologyTissue culture for neoplastic disorders, lymphocyte
88233PathologyTissue culture for neoplastic disorders, skin/tissue biopsy
88237PathologyTissue culture for neoplastic disorders, bone marrow/blood
88262PathologyChromosome analysis; 15-20 cells, 2 karyotypes
88271PathologyMolecular cytogenetics; DNA probe, each
88280PathologyChromosome analysis; additional karyotypes, each study
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